Neurexin-1 and Frontal Lobe White Matter: An Overlapping Intermediate Phenotype for Schizophrenia and Autism Spectrum Disorders

BACKGROUND: Structural variation in the neurexin-1 (NRXN1) gene increases risk for both autism spectrum disorders (ASD) and schizophrenia. However, the manner in which NRXN1 gene variation may be related to brain morphology to confer risk for ASD or schizophrenia is unknown. METHOD/PRINCIPAL FINDING...

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Detalhes bibliográficos
Main Authors: Voineskos, Aristotle N., Lett, Tristram A. P., Lerch, Jason P., Tiwari, Arun K., Ameis, Stephanie H., Rajji, Tarek K., Müller, Daniel J., Mulsant, Benoit H., Kennedy, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110800/
https://ncbi.nlm.nih.gov/pubmed/21687627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020982
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