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ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time

It was only 3 years ago that an acquired translocation of EML4 with ALK leading to the expression of an EML4-ALK oncoprotein in non-small cell lung cancer (NSCLC) was reported. Tumor cells expressing EML4-ALK are “addicted” to its continued function. Now, crizotinib, an oral ALK inhibitor, is demons...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gerber, David E., Minna, John D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110762/
https://ncbi.nlm.nih.gov/pubmed/21156280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.11.033
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