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Purified High Molecular Weight Synthetic Aβ(1-42) and Biological Aβ Oligomers are Equipotent in Rapidly Inducing MTT Formazan Exocytosis

Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse myoblast cell lines in a novel, modified MTT assay....

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Detalhes bibliográficos
Main Authors: Weidner, Adam M., Housley, Molly, Murphy, M. Paul, LeVine, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110692/
https://ncbi.nlm.nih.gov/pubmed/21504780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2011.03.082
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