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Interneuron loss reduces dendritic inhibition and GABA release in hippocampus of aged rats

Aging is associated with impairments in learning and memory and a greater incidence of limbic seizures. These changes in the aged brain have been associated with increased excitability of hippocampal pyramidal cells caused by a reduced number of GABAergic interneurons. To better understand these iss...

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Detalhes bibliográficos
Main Authors: Stanley, Emily M., Fadel, Jim R., Mott, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110542/
https://ncbi.nlm.nih.gov/pubmed/21277654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.12.014
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