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Bioreducible polymers with cell penetrating and endosome buffering functionality for gene delivery systems

Bioreducible cationic polymers (p(DAH(a)-R/API(b))s) composed of different ratios (a:b = 2:1, 1:1, 1:2) between arginine-grafted diaminohexane (DAH-R) (cell penetrating functionality) and 1-(3-aminopropyl) imidazole (API) (endosome buffering functionality) monomers were synthesized by Michael reacti...

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Detalhes bibliográficos
Main Authors: Kim, Tae-il, Rothmund, Thomas, Kissel, Thomas, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110531/
https://ncbi.nlm.nih.gov/pubmed/21352876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.02.013
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