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Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma

PURPOSE: We recently demonstrated that molecular therapy using aminoglycosides can overcome the underlying genetic defect in two zebrafish models of ocular coloboma and showed abnormal cell death to be a key feature associated with the optic fissure closure defects. In further studies to identify mo...

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Detalhes bibliográficos
Main Authors: Gregory-Evans, Cheryl Y., Moosajee, Mariya, Shan, Xianghong, Gregory-Evans, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110494/
https://ncbi.nlm.nih.gov/pubmed/21677791
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