Orange Juice and Its Component, Hesperidin, Decrease the Expression of Multidrug Resistance-Associated Protein 2 in Rat Small Intestine and Liver

We investigated the effects of orange juice (OJ) or hesperidin, a component of OJ, on the pharmacokinetics of pravastatin (PRV) and the expression of both protein and mRNA of multidrug resistance-associated protein 2 (Mrp2) in the rat small intestine and liver. Eight-week-old male Sprague-Dawley rat...

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Main Authors: Watanabe, Minoru, Matsumoto, Naoki, Takeba, Yuko, Kumai, Toshio, Tanaka, Masami, Tatsunami, Shinobu, Takenoshita-Nakaya, Sachiko, Harimoto, Yoshie, Kinoshita, Yuichi, Kobayashi, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110312/
https://ncbi.nlm.nih.gov/pubmed/21660137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/502057
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