Unexpected Accumulation of ncm(5)U and ncm(5)s(2)U in a trm9 Mutant Suggests an Additional Step in the Synthesis of mcm(5)U and mcm(5)s(2)U

BACKGROUND: Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the maturation process, a subset of the nucleosides are modified. Modifications in the anticodon region often modulate the decoding ability of the tRNA. At position 34, the majori...

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Hlavní autoři: Chen, Changchun, Huang, Bo, Anderson, James T., Byström, Anders S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110198/
https://ncbi.nlm.nih.gov/pubmed/21687733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020783
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