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Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay

The vast landscape of environmental chemicals has motivated the need for alternative methods to traditional whole-animal bioassays in toxicity testing. Embryonic stem (ES) cells provide an in vitro model of embryonic development and an alternative method for assessing developmental toxicity. Here, w...

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Detalhes bibliográficos
Main Authors: Chandler, Kelly J., Barrier, Marianne, Jeffay, Susan, Nichols, Harriette P., Kleinstreuer, Nicole C., Singh, Amar V., Reif, David M., Sipes, Nisha S., Judson, Richard S., Dix, David J., Kavlock, Robert, Hunter, Edward S., Knudsen, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110185/
https://ncbi.nlm.nih.gov/pubmed/21666745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018540
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