Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: The TONIC Randomized Controlled Trial

CONTEXT: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in US children and adolescents and can present with advanced fibrosis or non-alcoholic steatohepatitis (NASH). No treatment has been established. OBJECTIVE: To determine whether children with NAFLD would impro...

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Autori principali: Lavine, Joel E., Schwimmer, Jeffrey B., Van Natta, Mark L., Molleston, Jean P., Murray, Karen F., Rosenthal, Philip, Abrams, Stephanie H., Scheimann, Ann O., Sanyal, Arun J., Chalasani, Naga, Tonascia, James, Ünalp, Aynur, Clark, Jeanne M., Brunt, Elizabeth M., Kleiner, David E., Hoofnagle, Jay H., Robuck, Patricia R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110082/
https://ncbi.nlm.nih.gov/pubmed/21521847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2011.520
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