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Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets
Imputation allows the inference of unobserved genotypes in low-density data sets, and is often used to test for disease association at variants that are poorly captured by standard genotyping chips (such as low-frequency variants). Although much effort has gone into developing the best imputation al...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110048/ https://ncbi.nlm.nih.gov/pubmed/21364697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.10 |
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