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Synthesis and Evaluation of Fluorinated Aporphines: Potential Positron Emission Tomography Ligands for D(2) Receptors
[Image: see text] The 2-fluoroalkoxy-substituted catechol-aporphines 6, 8a−f and 11-mono-hydroxyaporphines 11a−e were synthesized and found to have high in vitro affinity and selectivity for the dopamine D(2) receptors. The catechol aporphines, 8b and 8d, and the monohydroxy aporphines, 11a−d, were...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110009/ https://ncbi.nlm.nih.gov/pubmed/21666830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001689 |
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