Hypertonic Saline Therapy in Cystic Fibrosis: Do Population Shifts Caused by the Osmotic Sensitivity of Infecting Bacteria Explain the Effectiveness of this Treatment?

Cystic fibrosis (CF) is caused by a defect in the CF transmembrane regulator that leads to depletion and dehydration of the airway surface liquid (ASL) of the lung epithelium, providing an environment that can be infected by bacteria leading to increased morbidity and mortality. Pseudomonas aerugino...

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Detalhes bibliográficos
Main Authors: Williams, Huw D., Behrends, Volker, Bundy, Jacob G., Ryall, Ben, Zlosnik, James E. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109665/
https://ncbi.nlm.nih.gov/pubmed/21687721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2010.00120
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