Neuroendocrine regulation of Drosophila metamorphosis requires TGFβ/Activin signaling

In insects, initiation of metamorphosis requires a surge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic gland, the primary endocrine organ of juvenile larvae. Here, we show that blocking TGFβ/Activin signaling, specifically in the Drosophila prothoracic gland, resul...

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Bibliographic Details
Main Authors: Gibbens, Ying Y., Warren, James T., Gilbert, Lawrence I., O'Connor, Michael B.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109597/
https://ncbi.nlm.nih.gov/pubmed/21613324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063412
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