Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth

INTRODUCTION: MicroRNAs (miRNAs) are a class of small non-coding RNAs (20 to 24 nucleotides) that post-transcriptionally modulate gene expression. A key oncomir in carcinogenesis is miR-21, which is consistently up-regulated in a wide range of cancers. However, few functional studies are available f...

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Detalhes bibliográficos
Main Authors: Yan, Li Xu, Wu, Qi Nian, Zhang, Yan, Li, Yang Yang, Liao, Ding Zhun, Hou, Jing Hui, Fu, Jia, Zeng, Mu Sheng, Yun, Jing Ping, Wu, Qiu Liang, Zeng, Yi Xin, Shao, Jian Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109565/
https://ncbi.nlm.nih.gov/pubmed/21219636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2803
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