Detecting Gene Copy Number Fluctuations in Tumor Cells by Microarray Analysis of Genomic Representations

In this work, we explore the use of representations in conjunction with DNA microarray technology to measure gene copy number changes in cancer. We demonstrate that arrays of DNA probes derived from low-complexity representations can be used to detect amplifications, deletions, and polymorphic diffe...

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Bibliografiska uppgifter
Huvudupphovsmän: Lucito, Robert, West, Joseph, Reiner, Andrew, Alexander, Joan, Esposito, Diane, Mishra, Bhubaneswar, Powers, Scott, Norton, Larry, Wigler, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2000
Ämnen:
Letter
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC310939/
https://ncbi.nlm.nih.gov/pubmed/11076858
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