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Implications of Molecular Heterogeneity for the Cooperativity of Biological Macromolecules
Cooperativity, a universal property of biological macromolecules, is typically characterized by a Hill slope, which can provide fundamental information about binding sites and interactions. We demonstrate, via simulations and single molecule FRET experiments, that molecular heterogeneity lowers bulk...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109240/ https://ncbi.nlm.nih.gov/pubmed/21572445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2052 |
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