Targeted Terminal Deletions as a Tool for Functional Genomics Studies in Plasmodium

We describe a transfection system that induces terminal deletions at specific chromosome ends in malaria parasites using a linear construct containing telomeric repeats at one end and plasmodial sequences able to drive homologous recombination at the other. A site-specific deletion was generated at...

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Hlavní autoři: Pace, Tomasino, Scotti, Raffaella, Janse, Chris J., Waters, Andrew P., Birago, Cecilia, Ponzi, Marta
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2000
Témata:
Methods
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310916/
https://ncbi.nlm.nih.gov/pubmed/10984459
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