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Human and Mouse Gene Structure: Comparative Analysis and Application to Exon Prediction

We describe a novel analytical approach to gene recognition based on cross-species comparison. We first undertook a comparison of orthologous genomic loci from human and mouse, studying the extent of similarity in the number, size and sequence of exons and introns. We then developed an approach for...

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Main Authors: Batzoglou, Serafim, Pachter, Lior, Mesirov, Jill P., Berger, Bonnie, Lander, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC310911/
https://ncbi.nlm.nih.gov/pubmed/10899144
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