Active Conservation of Noncoding Sequences Revealed by Three-Way Species Comparisons

Human and mouse genomic sequence comparisons are being increasingly used to search for evolutionarily conserved gene regulatory elements. Large-scale human–mouse DNA comparison studies have discovered numerous conserved noncoding sequences of which only a fraction has been functionally investigated...

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Autors principals: Dubchak, Inna, Brudno, Michael, Loots, Gabriela G., Pachter, Lior, Mayor, Chris, Rubin, Edward M., Frazer, Kelly A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310906/
https://ncbi.nlm.nih.gov/pubmed/10984448
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