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Mitochondrial DNA Damage and Repair in RPE Associated with Aging and Age-Related Macular Degeneration
PURPOSE. Mitochondrial DNA (mtDNA) damage may be associated with age-related diseases, such as age-related macular degeneration (AMD). The present study was designed to test whether the frequency of mtDNA damage, heteroplasmic mtDNA mutations, and repair capacity correlate with progression of AMD. M...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109040/ https://ncbi.nlm.nih.gov/pubmed/21273542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6163 |
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