Use of an Adult Rat Retinal Explant Model for Screening of Potential Retinal Ganglion Cell Neuroprotective Therapies

PURPOSE. To validate an established adult organotypic retinal explant culture system for use as an efficient medium-throughput screening tool to investigate novel retinal ganglion cell (RGC) neuroprotective therapies. METHODS. Optimal culture conditions for detecting RGC neuroprotection in rat retin...

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Main Authors: Bull, Natalie D., Johnson, Thomas V., Welsapar, Guncha, DeKorver, Nicholas W., Tomarev, Stanislav I., Martin, Keith R.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109030/
https://ncbi.nlm.nih.gov/pubmed/21345987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6873
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