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Hyperosmotic Stress-Induced Corneal Epithelial Cell Death through Activation of Polo-like Kinase 3 and c-Jun
PURPOSE. Hyperosmotic stress causes cell shrinkage, perturbs cell function, and damages DNA, resulting in cell cycle arrest and apoptosis. In the present study, the authors explore the mechanism involving hyperosmotic stress-induced activation of c-Jun/AP-1 through a novel Plk3 pathway in human corn...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109023/ https://ncbi.nlm.nih.gov/pubmed/21296815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6485 |
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