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Smad4 Is Required Predominantly in the Developmental Processes Dependent on the BMP Branch of the TGF-β Signaling System in the Embryonic Mouse Retina
PURPOSE. The present study was aimed at defining developmental roles of Smad4, a key mediator of the TGF-β superfamily signaling system, in the embryonic mouse retina. METHODS. Using a Cre/loxP-mediated conditional gene targeting approach, Smad4 gene function was deleted from the embryonic mouse ret...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109008/ https://ncbi.nlm.nih.gov/pubmed/21273545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5940 |
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