Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease

3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger, provides neuroprotection in stroke models and patients. In this study, we investigated its neuroprotective effects in a chronic rotenone rat model for Parkinson's disease. Here we showed that a five-week treat...

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Bibliografiske detaljer
Main Authors: Xiong, Nian, Xiong, Jing, Khare, Ghanshyam, Chen, Chunnuan, Huang, Jinsha, Zhao, Ying, Zhang, Zhentao, Qiao, Xian, Feng, Yuan, Reesaul, Harrish, Zhang, Yongxue, Sun, Shenggang, Lin, Zhicheng, Wang, Tao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108992/
https://ncbi.nlm.nih.gov/pubmed/21677777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020677
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