WFDC1 expression identifies memory CD4 T- lymphocytes rendered vulnerable to cell-cell HIV-1 transfer by promoting intercellular adhesive junctions

BACKGROUND: Elucidating mechanisms that promote HIV-1 transfer between CD4(+ )T-lymphocytes and their subsequent loss is of importance to HIV-1 pathogenesis. We recently reported that whey acidic protein, ps20, promotes cell-free HIV-1 spread through ICAM-1 modulation. Since ICAM-1 is pivotal in cel...

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Bibliografiska uppgifter
Huvudupphovsmän: Alvarez, Raymond A, Thorborn, Georgina, Reading, James L, Reddy, Shalini Kamu, Vyakarnam, Annapurna
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108927/
https://ncbi.nlm.nih.gov/pubmed/21545747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-29
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