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Prevention of NSAID-related upper gastrointestinal toxicity: a meta-analysis of traditional NSAIDs with gastroprotection and COX-2 inhibitors

BACKGROUND: Traditional NSAIDs (tNSAIDs) and COX-2 inhibitors (COX-2s) are important agents for the treatment of a variety or arthritic conditions. The purpose of this study was to systematically review the effectiveness of misoprostol, H2-receptor antagonists (H2RAs), and proton pump inhibitors (PP...

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Detalhes bibliográficos
Main Authors: Rostom, Alaa, Muir, Katherine, Dube, Catherine, Lanas, Angel, Jolicoeur, Emilie, Tugwell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108684/
https://ncbi.nlm.nih.gov/pubmed/21701610
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