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Congenic Mapping of the Type 1 Diabetes Locus, Idd3, to a 780-kb Region of Mouse Chromosome 3: Identification of a Candidate Segment of Ancestral DNA by Haplotype Mapping
Type 1 diabetes in the nonobese diabetic (NOD) mouse arises as a consequence of T cell-mediated destruction of the insulin-producing β cells of the pancreas. Although little is known of the events that initiate and subsequently drive β-cell destruction it is clear that the entire process is under co...
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Autores principales: | , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Cold Spring Harbor Laboratory Press
2000
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310860/ https://ncbi.nlm.nih.gov/pubmed/10779485 |
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