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Pleiotropic Effects of Glitazones: A Double Edge Sword?
Glitazones (thiazolidinediones) are drugs used for diabetes mellitus type 2. By binding to peroxisome proliferator-activated receptor γ (PPARγ) they modulate transcription of genes of carbohydrate and lipid metabolism. Through PPARγ stimulation, however, glitazones also affect other genes, encompass...
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Research Foundation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108480/ https://ncbi.nlm.nih.gov/pubmed/21687509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00014 |
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