Chemotherapy-Induced Genotoxic Stress Promotes Sensitivity to Natural Killer Cell Cytotoxicity by Enabling Missing-Self Recognition

Natural killer (NK) cells can recognize and kill tumor cells lacking “self” markers, such as class I MHC, but the basis for this recognition is not completely understood. NKR-P1 receptors are members of the C-type lectin-related NK receptor superfamily that are conserved from rodents to humans. Iden...

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Huvudupphovsmän: Fine, Jason H., Chen, Peter, Mesci, Aruz, Allan, David S.J., Gasser, Stephan, Raulet, David H., Carlyle, James R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108335/
https://ncbi.nlm.nih.gov/pubmed/20823164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1316
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