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Successful Treatment of Castleman’s Disease with Interleukin-1 Receptor Antagonist (Anakinra)

Castleman’s disease (CD) is a very rare lymphoproliferative disorder whose underlying pathophysiology is not fully understood and for which no standard treatment exists. Because interleukin-1 (IL-1) might promote the production of interleukin-6 (IL-6), a key pathogenic factor for the disease, we hyp...

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Bibliographic Details
Main Authors: El-Osta, Hazem, Janku, Filip, Kurzrock, Razelle
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108331/
https://ncbi.nlm.nih.gov/pubmed/20501803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0156
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