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Human TSC2–Null Fibroblast-Like Cells Induce Hair Follicle Neogenesis and Hamartoma Morphogenesis

Hamartomas are composed of cells native to an organ but abnormal in number, arrangement, or maturity. In tuberous sclerosis complex (TSC), hamartomas develop in multiple organs due to mutations of TSC1 or TSC2. Here we show that TSC2-null fibroblast-like cells grown from human TSC skin hamartomas in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Shaowei, Thangapazham, Rajesh L., Wang, Ji-an, Rajesh, Sangeetha, Kao, Tzu-Cheg, Sperling, Leonard, Moss, Joel, Darling, Thomas N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108033/
https://ncbi.nlm.nih.gov/pubmed/21407201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1236
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