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PEL: an unbiased method for estimating age-dependent genetic disease risk from pedigree data unselected for family history
Providing valid risk estimates of a genetic disease with variable age of onset is a major challenge for prevention strategies. When data are obtained from pedigrees ascertained through affected individuals, an adjustment for ascertainment bias is necessary. This paper focuses on ascertainment throug...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley-Liss
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108000/ https://ncbi.nlm.nih.gov/pubmed/19089844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20390 |
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