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Cell Type Specific Sequestration of Choline Acetyltransferase and Tyrosine Hydroxylase within Lewy bodies

Lewy bodies (LBs), the pathological hallmark of Lewy body disease (LBD), contain α-synuclein, as well as other proteins. In this study, we examined the relationship of α-synuclein to two rate-limiting enzymes in neurotransmitter synthesis, tyrosine hydroxylase (TH), and choline acetyltransferase (Ch...

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Detalhes bibliográficos
Main Authors: Dugger, Brittany N., Dickson, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107979/
https://ncbi.nlm.nih.gov/pubmed/20721565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0739-1
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