Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma

AIMS: To define the occurrence of KRAS and BRAF mutations, microsatellite instability (MSI), and MGMT and hMLH1 methylation and expression in colorectal serrated adenocarcinoma. METHODS AND RESULTS: KRAS codon 12/13 and 59/61 and BRAF V600E mutations, MSI, and MGMT and hMLH1 methylation and expressi...

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Autori principali: Stefanius, Karoliina, Ylitalo, Laura, Tuomisto, Anne, Kuivila, Rami, Kantola, Tiina, Sirniö, Päivi, Karttunen, Tuomo J, Mäkinen, Markus J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2011
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107946/
https://ncbi.nlm.nih.gov/pubmed/21457162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2559.2011.03821.x
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