Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein

In a bioinformatics-based screen for cellular genes that enhance Zaire ebolavirus (ZEBOV) transduction, AXL mRNA expression strongly correlated with ZEBOV infection. A series of cell lines and primary cells were identified that require Axl for optimal ZEBOV entry. Using one of these cell lines, we i...

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Huvudupphovsmän: Brindley, Melinda A., Hunt, Catherine L., Kondratowicz, Andrew S., Bowman, Jill, Sinn, Patrick L., McCray, Paul B., Quinn, Kathrina, Weller, Melodie L., Chiorini, John A., Maury, Wendy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107944/
https://ncbi.nlm.nih.gov/pubmed/21529875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.04.002
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