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Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy

Targeting the HIV entry and assembly pathways holds promise for development of novel anti-HIV gene therapy vectors. We characterized discrete dominant negative (DN) Gag and Envelope mutants for their anti HIV-1 activity. We show here that capsid mutants (Q155N and Y164A) are more potent inhibitors o...

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Detalhes bibliográficos
Main Authors: Joshi, Anjali, Garg, Himanshu, Ablan, Sherimay, Freed, Eric O, Nagashima, Kunio, Manjunath, N., Shankar, Premlata
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107932/
https://ncbi.nlm.nih.gov/pubmed/21529874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.03.028
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