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Protease inhibitors as possible pitfalls in proteomic analyses of complex biological samples
Sample preparation, especially protein and peptide fractionation prior to identification by mass spectrometry (MS) are typically applied to reduce sample complexity. The second key element in this process is proteolytic digestion that is performed mostly by trypsin. Optimization of this step is an i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107918/ https://ncbi.nlm.nih.gov/pubmed/21333769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.02.010 |
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