Global Hypomethylation Identifies Loci Targeted for Hypermethylation in Head and Neck Cancer

PURPOSE: The human epigenome is profoundly altered in cancers, with a characteristic loss of methylation in repetitive regions and concomitant accumulation of gene-promoter methylation. The degree to which these processes are coordinated is unclear so we investigated both in head and neck squamous c...

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Hauptverfasser: Poage, Graham M., Houseman, E. Andres, Christensen, Brock C., Butler, Rondi A., Avissar-Whiting, Michele, McClean, Michael D., Waterboer, Tim, Pawlita, Michael, Marsit, Carmen J., Kelsey, Karl T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107873/
https://ncbi.nlm.nih.gov/pubmed/21505061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0044
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