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2-hydroxylated sphingomyelin profiles in cells from patients with mutated fatty acid 2-hydroxylase

Fatty acid 2-hydroxylase (FA2H) is the enzyme responsible for the hydroxylation of free fatty acids prior to their incorporation into 2-hydroxylated sphingolipids, which are the major constituents of the myelin leaflet. Mutated FA2H has been associated with neurodegenerative diseases. Decreased FA2H...

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Detalhes bibliográficos
Main Authors: Dan, Phyllis, Edvardson, Simon, Bielawski, Jacek, Hama, Hiroko, Saada, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107802/
https://ncbi.nlm.nih.gov/pubmed/21599921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-84
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