mRNA Expression Signature of Gleason Grade Predicts Lethal Prostate Cancer

PURPOSE: Prostate-specific antigen screening has led to enormous overtreatment of prostate cancer because of the inability to distinguish potentially lethal disease at diagnosis. We reasoned that by identifying an mRNA signature of Gleason grade, the best predictor of prognosis, we could improve pre...

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Hlavní autoři: Penney, Kathryn L., Sinnott, Jennifer A., Fall, Katja, Pawitan, Yudi, Hoshida, Yujin, Kraft, Peter, Stark, Jennifer R., Fiorentino, Michelangelo, Perner, Sven, Finn, Stephen, Calza, Stefano, Flavin, Richard, Freedman, Matthew L., Setlur, Sunita, Sesso, Howard D., Andersson, Swen-Olof, Martin, Neil, Kantoff, Philip W., Johansson, Jan-Erik, Adami, Hans-Olov, Rubin, Mark A., Loda, Massimo, Golub, Todd R., Andrén, Ove, Stampfer, Meir J., Mucci, Lorelei A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2011
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107753/
https://ncbi.nlm.nih.gov/pubmed/21537050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.32.6421
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