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Vanoxerine: Cellular Mechanism of a New Antiarrhythmic

INTRODUCTION: There remains an unmet need for safe and effective antiarrhythmic drugs, especially for the treatment of atrial fibrillation. Vanoxerine is a drug that is free of adverse cardiac events in normal volunteers, yet is a potent blocker of the hERG (hK(v)11.1) cardiac potassium channel. Con...

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Detalles Bibliográficos
Main Authors: Lacerda, Antonio E., Kuryshev, Yuri A., Yan, Gan-Xin, Waldo, Albert L., Brown, Arthur M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107714/
https://ncbi.nlm.nih.gov/pubmed/19817928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2009.01623.x
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