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Coupling In vitro and In vivo Paradigm Reveals a Dose Dependent Inhibition of Angiogenesis Followed by Initiation of Autophagy by C6-Ceramide

The activity of N-hexanoyl-D-erythro-sphingosine, a C6-ceramide against angiogenesis was tested in vitro and in vivo. The effect of ceramide in inhibiting MCF-7 cancer cells was also determined. The aim of this study was to potentiate the effect of ceramide as anti-angiogenic compound that can regul...

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Detalhes bibliográficos
Main Authors: Bansode, Rishipal R., Ahmedna, Mohamed, Svoboda, Kurt R., Losso, Jack N.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107471/
https://ncbi.nlm.nih.gov/pubmed/21647331
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