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Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junction

T cell egress from the thymus is essential for adaptive immunity, yet the requirements for and sites of egress are incompletely understood. We have shown that transgenic expression of sphingosine-1-phosphate receptor-1 (S1P1) in immature thymocytes leads to their perivascular accumulation and premat...

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Detalhes bibliográficos
Main Authors: Zachariah, Marcus A., Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107339/
https://ncbi.nlm.nih.gov/pubmed/20413455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188222
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