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Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans

Antiinflammatory drugs achieve their therapeutic actions at least in part by regulation of cytokine formation. A “cytokine hypothesis” of depression is supported by the observation that depressed individuals have elevated plasma levels of certain cytokines compared with healthy controls. Here we inv...

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Bibliografiske detaljer
Main Authors: Warner-Schmidt, Jennifer L., Vanover, Kimberly E., Chen, Emily Y., Marshall, John J., Greengard, Paul
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107316/
https://ncbi.nlm.nih.gov/pubmed/21518864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104836108
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