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Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans

Antiinflammatory drugs achieve their therapeutic actions at least in part by regulation of cytokine formation. A “cytokine hypothesis” of depression is supported by the observation that depressed individuals have elevated plasma levels of certain cytokines compared with healthy controls. Here we inv...

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Detalhes bibliográficos
Main Authors: Warner-Schmidt, Jennifer L., Vanover, Kimberly E., Chen, Emily Y., Marshall, John J., Greengard, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107316/
https://ncbi.nlm.nih.gov/pubmed/21518864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104836108
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