Transmigration of Melanoma Cells through the Blood-Brain Barrier: Role of Endothelial Tight Junctions and Melanoma-Released Serine Proteases

Malignant melanoma represents the third common cause of brain metastasis, having the highest propensity to metastasize to the brain of all primary neoplasms in adults. Since the central nervous system lacks a lymphatic system, the only possibility for melanoma cells to reach the brain is via the blo...

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Detalhes bibliográficos
Main Authors: Fazakas, Csilla, Wilhelm, Imola, Nagyőszi, Péter, Farkas, Attila E., Haskó, János, Molnár, Judit, Bauer, Hannelore, Bauer, Hans-Christian, Ayaydin, Ferhan, Dung, Ngo Thi Khue, Siklós, László, Krizbai, István A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107231/
https://ncbi.nlm.nih.gov/pubmed/21674054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020758
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