Urinary pH, cigarette smoking and bladder cancer risk

Glucuronide conjugates of 4-aminobiphenyl and its N-hydroxy metabolite can be rapidly hydrolyzed in acidic urine to undergo further metabolic activation and form DNA adducts in the urothelium. We conducted a large multicenter case–control study in Spain to explore the etiology of bladder cancer and...

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Détails bibliographiques
Auteurs principaux: Alguacil, Juan, Kogevinas, Manolis, Silverman, Debra T., Malats, Núria, Real, Francisco X., García-Closas, Montserrat, Tardón, Adonina, Rivas, Manuel, Torà, Montserrat, García-Closas, Reina, Serra, Consol, Carrato, Alfredo, Pfeiffer, Ruth M., Fortuny, Joan, Samanic, Claudine, Rothman, Nathaniel
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Molecular Epidemiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106435/
https://ncbi.nlm.nih.gov/pubmed/21402590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr048
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