Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition

There is an urgent clinical need for chemotherapeutic and chemopreventive drugs for triple-negative breast cancer (TNBCa). Extending on our recent work, we hypothesize that the herbal compound 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) can inhibit the growth and metastasis of TNBCa xenograft and...

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Detalhes bibliográficos
Main Authors: Lee, Hyo-Jeong, Seo, Nam-Jun, Jeong, Soo-Jin, Park, Yongjin, Jung, Deok-Beom, Koh, Wonil, Lee, Hyo-Jung, Lee, Eun-Ok, Ahn, Kwang Seok, Ahn, Kyoo Seok, Lü, Junxuan, Kim, Sung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106430/
https://ncbi.nlm.nih.gov/pubmed/21289371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr015
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