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A single amino-acid substitution in the Ets domain alters core DNA binding specificity of Ets1 to that of the related transcription factors Elf1 and E74.

Ets proteins form a family of sequence specific DNA binding proteins which bind DNA through a 85 aminoacids conserved domain, the Ets domain, whose sequence is unrelated to any other characterized DNA binding domain. Unlike all other known Ets proteins, which bind specific DNA sequences centered ove...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Bosselut, R, Levin, J, Adjadj, E, Ghysdael, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1993
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8255775/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.22.5184
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