Reanalysis of Coreceptor Tropism in HIV-1–Infected Adults Using a Phenotypic Assay with Enhanced Sensitivity

The enhanced-sensitivity Trofile assay (TF-ES; Monogram Biosciences) was used to retest coreceptor tropism samples from 4 different cohorts of HIV-1–infected patients. Nine percent to 26% of patients with CCR5-tropic virus by the original Trofile assay had CXCR4-using virus by TF-ES. Lower CD4 cell...

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Bibliographische Detailangaben
Hauptverfasser: Wilkin, Timothy J., Goetz, Mathew Bidwell, Leduc, Robert, Skowron, Gail, Su, Zhaohui, Chan, Ellen S., Heera, Jayyant, Chapman, Doug, Spritzler, John, Reeves, Jacqueline D., Gulick, Roy M., Coakley, Eoin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
HIV/AIDS
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106234/
https://ncbi.nlm.nih.gov/pubmed/21427401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cir072
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